Predmint-16(For Various Cortico-Steroid responsive conditions)



Ingredients: Methylprednisolone 16mg tablets

Indications: Psoriasis, Psoriatic arthritis, Asthma, Rheumatoid arthritis, Ulcerative Colitis, and, Leukemia

Price: Rs.93 per strip 10 x 10 tablets

Medicine Description: Methylprednisolone family of products include methylprednisolone, methylprednisolone acetate and methylprednisolone sodium acetate (Solu-medrol). They will be called methylprednisolone in this monograph. They are synthetic (man-made) corticosteroids. Corticosteroids are naturally-occurring chemicals produced by the adrenal glands located adjacent to the kidneys. Corticosteroids affect metabolism in various ways and modify the immune system. Corticosteroids also block inflammation and are used in a wide variety of inflammatory diseases affecting many organs.

The FDA approved methylprednisolone in October 1957.

Medicinal Benefits: Methylprednisolone is used to achieve prompt suppression of inflammation such as rheumatoid arthritis, systemic lupus erythematosus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and, Crohn’s disease. Severe allergic conditions that fail conventional treatment may also respond to methylprednisolone, such as bronchial asthma, allergic rhinitis, drug induced dermatitis, and contact and atopic dermatitis.

Chronic skin conditions treated with methylprednisolone include, dermatitis, herpetiformis, pemphigus, severe psoriasis, and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva, and optic nerves of the eyes are also treated with methylprednisolone. Methylprednisolone is used for treating shock and multiple sclerosis although their use in these conditions is controversial. Methylprednisolone has not been adequately evaluated in pregnant women and lactating mothers.

Instructions for use: This medicine should be taken with food as it prevents you from getting an upset stomach. The duration of the course and the dosage of the medication will completely depend on what you are being treated for. Always take the prescribed amount and no more than that. Do not take it often and do not stop the medicine abruptly. Inform your doctor if you feel any discomfort. And, inform the doctor if you are pregnant or are breastfeeding. Talk to your doctor if you experience mood swings, fits, and, other psychiatric problems including suicidal thoughts, if you have an infection and you are taking medicines to suppress the immune response, if you are experiencing visual disturbances and eye infections, if you are elderly and have a heart problem, have high blood pressure, cholesterol, blood clotting, liver and kidney diseases. In case you develop any skin allergy or rise in blood sugar levels you may be diabetic.

Side Effects: This medication may cause inflammation and swelling in different parts like the stomach, pancreas, and may also cause ulcers. Adolescents and children undergoing steroid medications must be observed for growth abnormalities since they can retard growth.

Some medications may alter the effectiveness of the medicine or this medicine may reduce the effectiveness of other medicines. Inform your doctor about all the medications, antibiotics, antihypertensive medications, oral contraceptives, antacids, or anti-diabetic medications. With immune-suppressers like Ciclosporin and tacrolimus, you may be likely to experience side-effects of either medications. Simultaneous use of painkillers could cause the risk of stomach bleeding. Medications used to treat muscle disorders such as distigmine, neostigmine, and, pancuronium may lead to muscle weakness. Also, avoid consuming grape-juice while taking this medicine as it may cause adverse effects.

This medication usually causes dizziness, drowsiness, and visual disturbances which could affect the ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery. Take this medicine with caution especially if you have a history of liver disease.

Things to Follow: stay hydrated, especially if you have cough or cold. Drink liquids at room temperature to alleviate cough, runny nose, and, sneezing. Acid reflux is the main cause of a cough and one of the easiest ways to treat this condition is to avoid foods that cause this acid reflux. The immune system is adversely affected due to stress and could raise the risk of being sick. Regular exercise, meditation, breathing, and progressive muscle relaxation techniques to alleviate stress, 7-9 hours of sleep, maintaining personal hygiene and avoiding getting in contact with allergens must be followed.

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